12 September 2025
Newport 20 - 27 Llandovery
13 September 2025
Bridgend 27 - 24 Carmarthen Quins
Ebbw Vale 36 - 17 Aberavon
Pontypool 25 - 13 Swansea
RGC 31 - 47 Cardiff
18 September 2025
Cardiff 33 - 36 Carmarthen Quins
20 September 2025
Aberavon 28 - 24 Newport
Bridgend 17 - 34 Ebbw Vale
Llandovery 34 - 31 Swansea
Pontypool 14 - 23 RGC
25 September 2025
Bridgend 35 - 37 Aberavon
27 September 2025
Carmarthen Quins 24 - 12 Pontypool
Ebbw Vale 60 - 20 Cardiff
Newport 40 - 42 Swansea
RGC 31 - 41 Llandovery
2 October 2025
Swansea 24 - 14 Newport
4 October 2025
Aberavon 26 - 36 Bridgend
Llandovery 36 - 35 RGC
Pontypool 24 - 21 Carmarthen Quins
16 October 2025
19:30 Ebbw Vale 40 - 22 Llandovery
18 October 2025
Cardiff 45 - 26 Aberavon
Carmarthen Quins 28 -26 Newport
Pontypool 43 -10 Bridgend
RGC 31 - 38 Swansea
23 October 2025
19:30 Llandovery 35-17 Bridgend
25 October 2025
Aberavon 45 -35 RGC
Cardiff 31 -3 Pontypool
Newport 12 - 5 Ebbw Vale
Swansea 14 - 17 Carmarthen Quins
30 October 2025
19:30 Pontypool v Aberavon
1 November 2025
Bridgend v Newport
Cardiff v Llandovery
Carmarthen Quins v RGC
Ebbw Vale v Swansea
8 November 2025
Bridgend v RGC
15 November 2025
RGC v Ebbw Vale
21 November 2025
19:30 Llandovery v Pontypool
19:30 Newport v Cardiff
22 November 2025
Aberavon v Carmarthen Quins
Swansea v Bridgend
27 November 2025
19:30 Ebbw Vale v Carmarthen Quins
28 November 2025
19:30 Pontypool v Newport
29 November 2025
Bridgend v RGC
Cardiff v Swansea
Llandovery v Aberavon
4 December 2025
19:30 Aberavon v Ebbw Vale
5 December 2025
19:30 Swansea v Pontypool
6 December 2025
Cardiff v RGC
Carmarthen Quins v Bridgend
Llandovery v Newport
11 December 2025
19:30 Carmarthen Quins v Cardiff
13 December 2025
Ebbw Vale v Bridgend
Newport v Aberavon
RGC v Pontypool
Swansea v Llandovery
20 December 2025
Carmarthen Quins v Llandovery
Ebbw Vale v Pontypool
Newport v RGC
Swansea v Aberavon
17:15 Cardiff v Bridgend
26 December 2025
Llandovery v Carmarthen Quins
27 December 2025
Aberavon v Swansea
Bridgend v Cardiff
Pontypool v Ebbw Vale
17:15 RGC v Newport
3 January 2026
Aberavon v Cardiff
Bridgend v Pontypool
Newport v Carmarthen Quins
Swansea v RGC
17:15 Llandovery v Ebbw Vale
21 March 2026
Bridgend v Llandovery
Carmarthen Quins v Swansea
Ebbw Vale v Newport
Pontypool v Cardiff
RGC v Aberavon
28 March 2026
Aberavon v Pontypool
Llandovery v Cardiff
Newport v Bridgend
RGC v Carmarthen Quins
Swansea v Ebbw Vale
4 April 2026
Bridgend v Swansea
Cardiff v Newport
Carmarthen Quins v Aberavon
Ebbw Vale v RGC
Pontypool v Llandovery
11 April 2026
Aberavon v Llandovery
Carmarthen Quins v Ebbw Vale
Newport v Pontypool
RGC v Bridgend
Swansea v Cardiff